Murine B cell development and antibody responses to model antigens are not impaired in the absence of the TNF receptor GITR.

The Glucocorticoid-Induced Tumor necrosis factor Receptor GITR, a member of the tumor necrosis factor receptor superfamily, has been shown to be important in modulating immune responses in the context of T cell immunity. B lymphocytes also express GITR, but a role of GITR in humoral immunity has not...

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Bibliographic Details
Main Authors: Lenka Sinik Teodorovic, Carlo Riccardi, Raul M Torres, Roberta Pelanda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3273462?pdf=render