Study on the role of FoxO1 in the regulation of osteoblastic metabolism by 1,25(OH)2D3 in a high glucose environment

Study on the role of FoxO1 in the regulation of osteoblastic metabolism by 1,25(OH)2D3 in a high glucose environment

Objective To explore the effect of 1,25(OH)2D3 on the regulation of bone metabolism in a high-glucose environment and to provide evidence for the possible regulatory mechanism of 1,25(OH)2D3 on osteoblasts in a high-glucose environment.Methods The osteoblast cell line MC3T3-E1 was cultured in 3 grou...

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Bibliographic Details
Main Authors: ZHOU Jiaqi, SHU Linjing, XIONG Yi, ZHANG Yixin, XIANG Lin, WU Yingying
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2020-01-01
Series:口腔疾病防治
Subjects:
osteoblast，
osteogenic differentiation，
hyperglycemia，
diabetes，
forkhead transcription factor 1(foxo1)，
proliferation，
1 25(oh)2d3，
vitamin d，
bone metabolism，
Online Access:http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2020.01.004

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http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2020.01.004

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