Explainable models of disease progression in ALS: Learning from longitudinal clinical data with recurrent neural networks and deep model explanation

Background and Objectives Deep neural networks recently become a popular tool in medical research to predict disease progression and unveil its underlying temporal phenotypes. While being well suited to study longitudinal clinical data and learn disease progression models, its application in clinica...

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Bibliographic Details
Main Authors: Marcel Müller, Marta Gromicho, Mamede de Carvalho, Sara C. Madeira
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computer Methods and Programs in Biomedicine Update
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666990021000173