Annexin A2 promotes the migration and invasion of human hepatocellular carcinoma cells in vitro by regulating the shedding of CD147-harboring microvesicles from tumor cells.

Annexin A2 promotes the migration and invasion of human hepatocellular carcinoma cells in vitro by regulating the shedding of CD147-harboring microvesicles from tumor cells.

It has been reported that Annexin A2 (ANXA2) is up-regulated in hepatocellular carcinoma (HCC), but the roles of ANXA2 in the migration and invasion of HCC cells have not been determined. In this study, we found that ANXA2-specific siRNA (si-ANXA2) significantly inhibited the migration and invasion...

Full description

Bibliographic Details
Main Authors: Wei Zhang, Pu Zhao, Xiu-Li Xu, Lei Cai, Zhen-Shun Song, Da-Yong Cao, Kai-Shan Tao, Wen-Ping Zhou, Zhi-Nan Chen, Ke-Feng Dou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741296?pdf=render

Internet

http://europepmc.org/articles/PMC3741296?pdf=render

Similar Items