In vitro cobalt-stimulated hypoxia-inducible factor-1 overexpression does not correlate with cancer risk from cobalt exposure in humans
Chemical-induced pulmonary carcinogenesis in humans is usually a multi-decade process. The average age at diagnosis of lung cancer in cigarette smokers, and mesothelioma in asbestos workers, is approximately 70. The carcinogenic process consists of genetic changes to normal cells usually sequenced a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2019-05-01
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Series: | Toxicology Research and Application |
Online Access: | https://doi.org/10.1177/2397847319850167 |