Region-specific astrogliosis: differential vessel formation contributes to different patterns of astrogliosis in the cortex and striatum

Abstract Brain injury causes astrocytes to become reactive (astrogliosis). In this study, we compared astrogliosis in acutely injured cortex and striatum of adult FVB/N mice induced by stereotaxic injection of ATP, a component of danger-associated molecular patterns (DAMPs). Interestingly, MR analys...

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Bibliographic Details
Main Authors: Haijie Yang, Jiawei An, Insup Choi, Kihwang Lee, Sang-Myun Park, Ilo Jou, Eun-Hye Joe
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-020-00642-0