Monitoring tumor response to the vascular disrupting agent CKD-516 in a rabbit VX2 intramuscular tumor model using PET/MRI: Simultaneous evaluation of vascular and metabolic parameters.

Monitoring tumor response to the vascular disrupting agent CKD-516 in a rabbit VX2 intramuscular tumor model using PET/MRI: Simultaneous evaluation of vascular and metabolic parameters.

To determine whether the CKD-516 produces a significant change in vascular and metabolic parameters in PET/MRI.With institutional Animal Care and Use Committee approval, 18 VX2 carcinoma tumors implanted in bilateral back muscles of 9 rabbits were evaluated. Serial PET/MRI were performed before, 4 h...

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Bibliographic Details
Main Authors: Su Yeon Ahn, Jin Mo Goo, Kyung Hee Lee, Seunggyun Ha, Jin Chul Paeng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5811032?pdf=render

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http://europepmc.org/articles/PMC5811032?pdf=render

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