The CYP2B6 G516T polymorphism influences CD4+ T-cell counts in HIV-positive patients receiving antiretroviral therapy in an ethnically diverse region of the Amazon

The CYP2B6 G516T polymorphism influences CD4+ T-cell counts in HIV-positive patients receiving antiretroviral therapy in an ethnically diverse region of the Amazon

Objectives: Cytochrome P450 (CYP) enzyme polymorphisms seem to significantly influence the variability of the responses to certain antiretroviral drugs and their toxicity levels. The objective of this study was to evaluate the influence of the CYP2B6 G516T polymorphism on hepatic, renal, immunologic...

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Bibliographic Details
Main Authors: Maria Alice Freitas Queiroz, Rogério Valois Laurentino, Ednelza da Silva Graça Amoras, Mauro Sérgio Moura de Araújo, Samara Tatielle Monteiro Gomes, Sandra Souza Lima, Antonio Carlos Rosário Vallinoto, Marluísa de Oliveira Guimarães Ishak, Ricardo Ishak, Luiz Fernando Almeida Machado
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:International Journal of Infectious Diseases
Subjects:
HIV-1
CYP2B6
Miscegenation
Antiretroviral drugs
Treatment response
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971216316459

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http://www.sciencedirect.com/science/article/pii/S1201971216316459

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