Intestinal Epithelial Cell-Derived Extracellular Vesicles Modulate Hepatic Injury via the Gut-Liver Axis During Acute Alcohol Injury

Intestinal Epithelial Cell-Derived Extracellular Vesicles Modulate Hepatic Injury via the Gut-Liver Axis During Acute Alcohol Injury

Binge drinking, i.e., heavy episodic drinking in a short time, has recently become an alarming societal problem with negative health impact. However, the harmful effects of acute alcohol injury in the gut-liver axis remain elusive. Hence, we focused on the physiological and pathological changes and...

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Bibliographic Details
Main Authors: Arantza Lamas-Paz, Laura Morán, Jin Peng, Beatriz Salinas, Nuria López-Alcántara, Svenja Sydor, Ramiro Vilchez-Vargas, Iris Asensio, Fengjie Hao, Kang Zheng, Beatriz Martín-Adrados, Laura Moreno, Angel Cogolludo, Manuel Gómez del Moral, Lars Bechmann, Eduardo Martínez-Naves, Javier Vaquero, Rafael Bañares, Yulia A. Nevzorova, Francisco Javier Cubero
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
hepatocytes
intestinal epithelial cells
extracellular vesicles
alcohol (EtOH)
gut-liver axis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.603771/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.603771/full

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