Chimerization Enables Gene Synthesis and Lentiviral Delivery of Customizable TALE-Based Effectors

Designer effectors based on the DNA binding domain (DBD) of <i>Xanthomonas</i> transcription activator-like effectors (TALEs) are powerful sequence-specific tools with an excellent reputation for their specificity in editing the genome, transcriptome, and more recently the epigenome in m...

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Bibliographic Details
Main Authors: Yongxing Fang, Wladislaw Stroukov, Toni Cathomen, Claudio Mussolino
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/3/795