Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch.

Hypoxia-induced cell injury has been related to multiple pathological conditions. In order to render hypoxia-sensitive cells and tissues resistant to low O2 environment, in this current study, we used Drosophila melanogaster as a model to dissect the mechanisms underlying hypoxia-tolerance. A D. mel...

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Bibliographic Details
Main Authors: Dan Zhou, Jin Xue, James C K Lai, Nicholas J Schork, Kevin P White, Gabriel G Haddad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2556400?pdf=render