Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells

Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells

Feng Wang,1,2 Hai Li,3 Xiao-Gang Yan,4 Zhi-Wei Zhou,2 Zhi-Gang Yi,5 Zhi-Xu He,6 Shu-Ting Pan,7 Yin-Xue Yang,3 Zuo-Zheng Wang,1 Xueji Zhang,8 Tianxing Yang,9 Jia-Xuan Qiu,7 Shu-Feng Zhou21Department of Hepatobiliary Surgery, General Hospital, Ningxia Medical University, Yinchuan, People’s...

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Bibliographic Details
Main Authors: Wang F, Li H, Yan XG, Zhou ZW, Yi ZG, He ZX, Pan ST, Yang YX, Wang ZZ, Zhang X, Yang T, Qiu JX, Zhou SF
Format: Article
Language:English
Published: Dove Medical Press 2015-01-01
Series:Drug Design, Development and Therapy
Online Access:http://www.dovepress.com/alisertib-induces-cell-cycle-arrest-and-autophagy-and-suppresses-epith-peer-reviewed-article-DDDT

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http://www.dovepress.com/alisertib-induces-cell-cycle-arrest-and-autophagy-and-suppresses-epith-peer-reviewed-article-DDDT

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