Load-independent effects of empagliflozin contribute to improved cardiac function in experimental heart failure with reduced ejection fraction

Load-independent effects of empagliflozin contribute to improved cardiac function in experimental heart failure with reduced ejection fraction

Abstract Background and aims Sodium–glucose linked cotransporter-2 (SGLT2) inhibitors reduce the likelihood of hospitalization for heart failure and cardiovascular death in both diabetic and non-diabetic individuals with reduced ejection fraction heart failure. Because SGLT2 inhibitors lead to volum...

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Bibliographic Details
Main Authors: Kim A. Connelly, Yanling Zhang, Jean-François Desjardins, Linda Nghiem, Aylin Visram, Sri N. Batchu, Verra G. Yerra, Golam Kabir, Kerri Thai, Andrew Advani, Richard E. Gilbert
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cardiovascular Diabetology
Subjects:
Sodium–glucose linked co-transporter 2 inhibitor
Heart failure reduced ejection fraction
Systole
Diastole
Online Access:https://doi.org/10.1186/s12933-020-0994-y

Internet

https://doi.org/10.1186/s12933-020-0994-y

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