Modulation of Hyperpolarization-Activated Inward Current and Thalamic Activity Modes by Different Cyclic Nucleotides

Modulation of Hyperpolarization-Activated Inward Current and Thalamic Activity Modes by Different Cyclic Nucleotides

The hyperpolarization-activated inward current, Ih, plays a key role in the generation of rhythmic activities in thalamocortical (TC) relay neurons. Cyclic nucleotides, like 3′,5′-cyclic adenosine monophosphate (cAMP), facilitate voltage-dependent activation of hyperpolarization-activated cyclic nuc...

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Bibliographic Details
Main Authors: Maia Datunashvili, Rahul Chaudhary, Mehrnoush Zobeiri, Annika Lüttjohann, Evanthia Mergia, Arnd Baumann, Sabine Balfanz, Björn Budde, Gilles van Luijtelaar, Hans-Christian Pape, Doris Koesling, Thomas Budde
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
thalamus
dLGN
cyclic nucleotides
NO-GC2
HCN channels
Ih current
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00369/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00369/full

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