Mitochondrial Transport and Turnover in the Pathogenesis of Amyotrophic Lateral Sclerosis
Neurons are high-energy consuming cells, heavily dependent on mitochondria for ATP generation and calcium buffering. These mitochondrial functions are particularly critical at specific cellular sites, where ionic currents impose a large energetic burden, such as at synapses. The highly polarized nat...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-05-01
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| Series: | Biology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-7737/8/2/36 |