A secretion-enhancing cis regulatory targeting element (SECReTE) involved in mRNA localization and protein synthesis.

The localization of mRNAs encoding secreted/membrane proteins (mSMPs) to the endoplasmic reticulum (ER) likely facilitates the co-translational translocation of secreted proteins. However, studies have shown that mSMP recruitment to the ER in eukaryotes can occur in a manner that is independent of t...

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Bibliographic Details
Main Authors: Osnat Cohen-Zontag, Camila Baez, Lisha Qiu Jin Lim, Tsviya Olender, Dvir Schirman, Dvir Dahary, Yitzhak Pilpel, Jeffrey E Gerst
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008248