Fat Mass Follows a U-Shaped Distribution Based on Estradiol Levels in Postmenopausal Women

ObjectiveEstradiol (E2) regulates adipose tissue resulting in increased fat mass (FM) with declining E2. However, increased visceral fat and hyperestrogenemia are features of obese individuals. It is possible that adipocytes in obese individuals are less sensitive to E2 resulting in higher FM. Our o...

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Bibliographic Details
Main Authors: Georgia Colleluori, Rui Chen, Nicola Napoli, Lina E. Aguirre, Clifford Qualls, Dennis T. Villareal, Reina Armamento-Villareal
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00315/full