Na+/Ca2+ Exchanger 1/2 Double-Heterozygote Knockout Mice Display Increased Nitric Oxide Component and Altered Colonic Motility

Na+/Ca2+ Exchanger 1/2 Double-Heterozygote Knockout Mice Display Increased Nitric Oxide Component and Altered Colonic Motility

The Na+/Ca2+ exchanger (NCX) is a plasma membrane transporter involved in regulating intracellular Ca2+ concentrations. NCX is critical for Ca2+ regulation in cardiac muscle, vascular smooth muscle, and nerve fibers. To determine the role of NCX1 and NCX2 in gastrointestinal tissues, we examined ele...

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Bibliographic Details
Main Authors: Kazuhiro Nishiyama, Yasu-Taka Azuma, Satomi Kita, Naoki Azuma, Satomi Hayashi, Hidemitsu Nakajima, Takahiro Iwamoto, Tadayoshi Takeuchi
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319302476

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http://www.sciencedirect.com/science/article/pii/S1347861319302476

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