Identification of thioredoxin glutathione reductase inhibitors that kill cestode and trematode parasites.

Identification of thioredoxin glutathione reductase inhibitors that kill cestode and trematode parasites.

Parasitic flatworms are responsible for serious infectious diseases that affect humans as well as livestock animals in vast regions of the world. Yet, the drug armamentarium available for treatment of these infections is limited: praziquantel is the single drug currently available for 200 million pe...

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Bibliographic Details
Main Authors: Fabiana Ross, Paola Hernández, Williams Porcal, Gloria V López, Hugo Cerecetto, Mercedes González, Tatiana Basika, Carlos Carmona, Martín Fló, Gabriela Maggioli, Mariana Bonilla, Vadim N Gladyshev, Mariana Boiani, Gustavo Salinas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335049?pdf=render

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http://europepmc.org/articles/PMC3335049?pdf=render

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