Mitochondrial matters: Mitochondrial bottlenecks, self-assembling structures, and entrapment in the female germline

Mitochondrial replacement therapy, a procedure to generate embryos with the nuclear genome of a donor mother and the healthy mitochondria of a recipient egg, has recently emerged as a promising strategy to prevent transmission of devastating mitochondrial DNA diseases and infertility. The procedure...

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Bibliographic Details
Main Author: Florence L. Marlow
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117300429