IFNG +874T/A polymorphism is not associated with American tegumentary leishmaniasis susceptibility but can influence <it>Leishmania </it>induced IFN-γ production

<p>Abstract</p> <p>Background</p> <p>Interferon-gamma is a key cytokine in the protective responses against intracellular pathogens. A single nucleotide polymorphism (SNP) located in the first intron of the human IFN-γ gene can putatively influence the secretion of cyto...

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Main Authors: Sampaio Elizabeth P, Pirmez Claude, Mattos Marise, Oliveira-Neto Manoel P, Amato Valdir S, Maniero Viviane C, Marques Fabiana, Gomes-Silva Adriano, Bittar Rita, Covas Claudia, Matos Guilherme, Moraes Milton O, Da-Cruz Alda
Format: Article
Language:English
Published: BMC 2007-04-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/7/33