Toxoplasma gondii infection in the brain inhibits neuronal degeneration and learning and memory impairments in a murine model of Alzheimer's disease.

Immunosuppression is a characteristic feature of Toxoplasma gondii-infected murine hosts. The present study aimed to determine the effect of the immunosuppression induced by T. gondii infection on the pathogenesis and progression of Alzheimer's disease (AD) in Tg2576 AD mice. Mice were infected...

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Main Authors: Bong-Kwang Jung, Kyoung-Ho Pyo, Ki Young Shin, Young Sang Hwang, Hyoungsub Lim, Sung Joong Lee, Jung-Ho Moon, Sang Hyung Lee, Yoo-Hun Suh, Jong-Yil Chai, Eun-Hee Shin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3310043?pdf=render