The Mechanism of Diarrhetic Shellfish Poisoning Toxin Production in Prorocentrum spp.: Physiological and Molecular Perspectives

Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disorder caused by the consumption of seafood contaminated with okadaic acid (OA) and dinophysistoxins (DTXs). OA and DTXs are potent inhibitors of protein phosphatases 2A, 1B, and 2B, which may promote cancer in the human digestive system....

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Bibliographic Details
Main Authors: Thomas Chun-Hung Lee, Fiona Long-Yan Fong, Kin-Chung Ho, Fred Wang-Fat Lee
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/10/272