Anti-inflammatory impact of minocycline in a mouse model of tauopathy

Alzheimer’s disease (AD) is characterised by the extracellular deposition of β-amyloid in senile plaques, the intraneuronal accumulation of hyperphosphorylated tau aggregates as neurofibrillary tangles, and progressive neuronal loss leading to the onset of dementia. Increasing evidence suggests that...

Full description

Bibliographic Details
Main Authors: Claire J Garwood, Jonathan D Cooper, Diane P Hanger, Wendy Noble
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-10-01
Series:Frontiers in Psychiatry
Subjects:
tau
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2010.00136/full