Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: Unraveling the genome to understand the mind

In mature, differentiated neurons in the central nervous system (CNS), epigenetic mechanisms—including DNA methylation, histone modification, and regulatory noncoding RNAs—play critical roles in encoding experience and environmental stimuli into stable, behaviorally meaningful changes in gene expres...

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Bibliographic Details
Main Authors: Jenny Hsieh, Amelia J. Eisch
Format: Article
Language:English
Published: Elsevier 2010-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110000100