Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in life

Savva et al. investigate the sex dependent effect of maternal obesity on the metabolism of offspring. They find that metabolic changes are conferred on a sex basis, with males suffering from impaired lipid metabolism relative to females when born to obese mothers, using a lipidomic approach.

Bibliographic Details
Main Authors: Christina Savva, Luisa A. Helguero, Marcela González-Granillo, Daniela Couto, Tânia Melo, Xidan Li, Bo Angelin, Maria Rosário Domingues, Claudia Kutter, Marion Korach-André
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01513-z