Kososan, a Kampo medicine, prevents a social avoidance behavior and attenuates neuroinflammation in socially defeated mice

Kososan, a Kampo medicine, prevents a social avoidance behavior and attenuates neuroinflammation in socially defeated mice

Abstract Background Kososan, a Kampo (traditional Japanese herbal) medicine, has been used for the therapy of depressive mood in humans. However, evidence for the antidepressant efficacy of kososan and potential mechanisms are lacking. Recently, it has been recognized that stress triggers neuroinfla...

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Bibliographic Details
Main Authors: Naoki Ito, Eiji Hirose, Tatsuya Ishida, Atsushi Hori, Takayuki Nagai, Yoshinori Kobayashi, Hiroaki Kiyohara, Tetsuro Oikawa, Toshihiko Hanawa, Hiroshi Odaguchi
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Neuroinflammation
Subjects:
Kampo
Kososan
Depression
Anxiety
Antidepressant-like effect
Chronic social defeat stress
Online Access:http://link.springer.com/article/10.1186/s12974-017-0876-8

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http://link.springer.com/article/10.1186/s12974-017-0876-8

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