Celastrol Protects against Antimycin A-Induced Insulin Resistance in Human Skeletal Muscle Cells

Celastrol Protects against Antimycin A-Induced Insulin Resistance in Human Skeletal Muscle Cells

Mitochondrial dysfunction and inflammation are widely accepted as key hallmarks of obesity-induced skeletal muscle insulin resistance. The aim of the present study was to evaluate the functional roles of an anti-inflammatory compound, celastrol, in mitochondrial dysfunction and insulin resistance in...

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Bibliographic Details
Main Authors: Mohamad Hafizi Abu Bakar, Kian-Kai Cheng, Mohamad Roji Sarmidi, Harisun Yaakob, Hasniza Zaman Huri
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Molecules
Subjects:
celastrol
mitochondrial dysfunction
inflammation
human skeletal muscle
nuclear factor kappa B
Online Access:http://www.mdpi.com/1420-3049/20/5/8242

Internet

http://www.mdpi.com/1420-3049/20/5/8242

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