Analysis of conventional and alternative CRISPR/Cas9 genome editing to enhance a single-base pair knock-in mutation

Abstract Background The use of CRISPR/Cas9 technologies in generating single-base pair knock-in mutations has recently exploded in the number of methods available. However, with the growing expansion of new technologies, it can be difficult to determine the best method for genome editing. Results In...

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Bibliographic Details
Main Authors: Carina Edmondson, Qi Zhou, Xuan Liu
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12896-021-00707-5