Structural and functional diversity of the microbial kinome.

The eukaryotic protein kinase (ePK) domain mediates the majority of signaling and coordination of complex events in eukaryotes. By contrast, most bacterial signaling is thought to occur through structurally unrelated histidine kinases, though some ePK-like kinases (ELKs) and small molecule kinases a...

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Bibliographic Details
Main Authors: Natarajan Kannan, Susan S Taylor, Yufeng Zhai, J Craig Venter, Gerard Manning
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0050017