Structural and functional diversity of the microbial kinome.
The eukaryotic protein kinase (ePK) domain mediates the majority of signaling and coordination of complex events in eukaryotes. By contrast, most bacterial signaling is thought to occur through structurally unrelated histidine kinases, though some ePK-like kinases (ELKs) and small molecule kinases a...
Main Authors: | Natarajan Kannan, Susan S Taylor, Yufeng Zhai, J Craig Venter, Gerard Manning |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-03-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.0050017 |
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