Synergistic suppression of the PI3K inhibitor CAL-101 with bortezomib on mantle cell lymphoma growth

Synergistic suppression of the PI3K inhibitor CAL-101 with bortezomib on mantle cell lymphoma growth

<b>Objective:</b>To investigate the effects of CAL-101, particularly when combined with bortezomib (BTZ) on mantle cell lymphoma (MCL) cells, and to explore its relative mechanisms.<br/><b>Methods:</b>MTT assay was applied to detect the inhibitory effects of different c...

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Bibliographic Details
Main Authors: Fu-Lian Qu, Bing Xia, Su-Xia Li, Chen Tian, Hong-Liang Yang, Qian Li, Ya-Fei Wang, Yong Yu, Yi-Zhuo Zhang
Format: Article
Language:English
Published: China Anti-Cancer Association 2015-12-01
Series:Cancer Biology & Medicine
Subjects:
CAL-101
bortezomib (BTZ)
phosphatidylinositol-3-kinase (PI3K)
mantle cell lymphoma (MCL)
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/894

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/894

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