Acute and long-term outcomes in a Drosophila melanogaster model of classic galactosemia occur independently of galactose-1-phosphate accumulation

Acute and long-term outcomes in a Drosophila melanogaster model of classic galactosemia occur independently of galactose-1-phosphate accumulation

Classic galactosemia (CG) is a potentially lethal inborn error of metabolism that results from the profound loss of galactose-1-phosphate uridylyltransferase (GALT), the second enzyme in the Leloir pathway of galactose metabolism. Neonatal detection and dietary restriction of galactose minimizes or...

Full description

Bibliographic Details
Main Authors: Jennifer M. I. Daenzer, Patricia P. Jumbo-Lucioni, Marquise L. Hopson, Kerry R. Garza, Emily L. Ryan, Judith L. Fridovich-Keil
Format: Article
Language:English
Published: The Company of Biologists 2016-11-01
Series:Disease Models & Mechanisms
Subjects:
Galactosemia
Drosophila
Gal-1P
Galactose
Online Access:http://dmm.biologists.org/content/9/11/1375

Internet

http://dmm.biologists.org/content/9/11/1375

Similar Items