Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity.
A relatively small number of signals are responsible for the variety and pattern of cell types generated in developing embryos. In part this is achieved by exploiting differences in the concentration or duration of signaling to increase cellular diversity. In addition, however, changes in cellular c...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-07-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC4098999?pdf=render |