A Novel Bioengineered Functional Motor Unit Platform to Study Neuromuscular Interaction

A Novel Bioengineered Functional Motor Unit Platform to Study Neuromuscular Interaction

Background: In many neurodegenerative and muscular disorders, and loss of innervation in sarcopenia, improper reinnervation of muscle and dysfunction of the motor unit (MU) are key pathogenic features. <i>In vivo</i> studies of MUs are constrained due to difficulties isolating and extrac...

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Bibliographic Details
Main Authors: Jasdeep Saini, Alessandro Faroni, Adam J. Reid, Kamel Mamchaoui, Vincent Mouly, Gillian Butler-Browne, Adam P. Lightfoot, Jamie S. McPhee, Hans Degens, Nasser Al-Shanti
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Clinical Medicine
Subjects:
motor unit (MU)
neuromuscular junction (NMJ)
motor neuron (MN) co-culture
myotube
human myoblast
Online Access:https://www.mdpi.com/2077-0383/9/10/3238

Internet

https://www.mdpi.com/2077-0383/9/10/3238

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