Glucocorticoid Therapy of Multiple Sclerosis Patients Induces Anti-inflammatory Polarization and Increased Chemotaxis of Monocytes

Glucocorticoid Therapy of Multiple Sclerosis Patients Induces Anti-inflammatory Polarization and Increased Chemotaxis of Monocytes

Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system (CNS), characterized by the infiltration of mononuclear cells into the CNS and a subsequent inflammation of the brain. Monocytes are implicated in disease pathogenesis not only in their function as potential antigen-prese...

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Bibliographic Details
Main Authors: Henrike J. Fischer, Tobias L. K. Finck, Hannah L. Pellkofer, Holger M. Reichardt, Fred Lühder
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
methylprednisolone therapy
monocytes
M2 polarization
chemokines
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01200/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01200/full

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