Ciona Brachyury proximal and distal enhancers have different FGF dose-response relationships.

Many genes are regulated by two or more enhancers that drive similar expression patterns. Evolutionary theory suggests that these seemingly redundant enhancers must have functionally important differences. In the simple ascidian chordate Ciona, the transcription factor Brachyury is induced exclusive...

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Bibliographic Details
Main Authors: Matthew J Harder, Julie Hix, Wendy M Reeves, Michael T Veeman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009305