Role of Copper in the Onset of Alzheimer’s Disease Compared to Other Metals

Alzheimer’s disease (AD) is a neurodegenerative disorder that is characterized by amyloid plaques in patients’ brain tissue. The plaques are mainly made of β-amyloid peptides and trace elements including Zn2+, Cu2+, and Fe2+. Some studies have shown that AD can be considered a type of metal dyshomeo...

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Bibliographic Details
Main Authors: Soghra Bagheri, Rosanna Squitti, Thomas Haertlé, Mariacristina Siotto, Ali A. Saboury
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00446/full