Ensemble models of neutrophil trafficking in severe sepsis.

A hallmark of severe sepsis is systemic inflammation which activates leukocytes and can result in their misdirection. This leads to both impaired migration to the locus of infection and increased infiltration into healthy tissues. In order to better understand the pathophysiologic mechanisms involve...

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Bibliographic Details
Main Authors: Sang Ok Song, Sang O K Song, Justin Hogg, Zhi-Yong Peng, Robert Parker, John A Kellum, Gilles Clermont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3297568?pdf=render