Dapagliflozin in patients with type 2 diabetes mellitus
Dapagliflozin is a selective and reversible inhibitor of sodium–glucose linked transporter type 2 (SGLT2), which mediates approximately 90% of active renal glucose reabsorption in the early proximal tubule of the kidney. Dapagliflozin significantly reduces glucose reabsorption and decreases serum gl...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2015-02-01
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Series: | Therapeutic Advances in Endocrinology and Metabolism |
Online Access: | https://doi.org/10.1177/2042018814558243 |