Dapagliflozin in patients with type 2 diabetes mellitus

Dapagliflozin is a selective and reversible inhibitor of sodium–glucose linked transporter type 2 (SGLT2), which mediates approximately 90% of active renal glucose reabsorption in the early proximal tubule of the kidney. Dapagliflozin significantly reduces glucose reabsorption and decreases serum gl...

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Bibliographic Details
Main Authors: Theodosios D. Filippatos, Evangelos N. Liberopoulos, Moses S. Elisaf
Format: Article
Language:English
Published: SAGE Publishing 2015-02-01
Series:Therapeutic Advances in Endocrinology and Metabolism
Online Access:https://doi.org/10.1177/2042018814558243