Efficacy and toxicity of once versus twice daily regimens of amikacin in febrile neutropenic pediatric cancer patients

Purpose: To compare the pharmacokinetic profile, clinical efficacy and toxicity of once-daily dosing of amikacin compared to twice-daily dosing among pediatric cancer patients with fever and neutropenia. Methods: 134 pediatric patients with hematological malignancies were randomly assigned to receiv...

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Bibliographic Details
Main Authors: Reda Abd-Elfattah, Alaa M.A. Elhdad, Ahmed Khames, Mohmed E.A. Abdelrahim, Samia A. Shouman
Format: Article
Language:English
Published: SpringerOpen 2017-03-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2314853516301354