Efficacy and toxicity of once versus twice daily regimens of amikacin in febrile neutropenic pediatric cancer patients
Purpose: To compare the pharmacokinetic profile, clinical efficacy and toxicity of once-daily dosing of amikacin compared to twice-daily dosing among pediatric cancer patients with fever and neutropenia. Methods: 134 pediatric patients with hematological malignancies were randomly assigned to receiv...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2017-03-01
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Series: | Beni-Suef University Journal of Basic and Applied Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2314853516301354 |