Relative Codon Adaptation Index, a Sensitive Measure of Codon Usage Bias

We propose a simple, sensitive measure of synonymous codon usage bias, the Relative Codon Adaptation Index (rCAI), as a way to discriminate better between highly biased and unbiased regions, compared with the widely used Codon Adaptation Index (CAI). CAI is a geometric mean of the relative usage of...

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Bibliographic Details
Main Authors: Soohyun Lee, Seyeon Weon, Sooncheol Lee, Changwon Kang
Format: Article
Language:English
Published: SAGE Publishing 2010-05-01
Series:Evolutionary Bioinformatics
Online Access:http://la-press.com/relative-codon-adaptation-index-a-sensitive-measure-of-codon-usage-bia-a2033