Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection

Guanylate-binding proteins (GBPs) are induced by the inflammatory cytokine interferon gamma (IFN-γ) and have been shown to be important factors in the defense of the intracellular pathogen Toxoplasma gondii. In previous studies, we showed that members of the mouse GBP family, such as mGBP2 and mGBP7...

Full description

Bibliographic Details
Main Authors: Nora Steffens, Cornelia Beuter-Gunia, Elisabeth Kravets, Artur Reich, Larissa Legewie, Klaus Pfeffer, Daniel Degrandi
Format: Article
Language:English
Published: American Society for Microbiology 2020-01-01
Series:mBio
Subjects:
guanylate-binding proteins
cell-autonomous immunity
toxoplasma gondii
host-pathogen interaction
interferons
mgbp7
Online Access:https://doi.org/10.1128/mBio.02993-19

Internet

https://doi.org/10.1128/mBio.02993-19

Similar Items