The Interplay of Genes with the Gut Microbiota in the Aetiopathogenesis of Spondyloarthropathies and Crohn’s Disease: Implications for Future Therapeutic Targets

The Interplay of Genes with the Gut Microbiota in the Aetiopathogenesis of Spondyloarthropathies and Crohn’s Disease: Implications for Future Therapeutic Targets

The phenotypical overlap between the spondyloarthropathies (SpA) and Crohn’s disease (CD) has long been recognised. More recently, the co-inheritance of these diseases and the existence of a plethora of shared genetic risk loci have been demonstrated by genealogic databases and genome-wide associati...

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Bibliographic Details
Main Authors: Simon M Stebbings, Rebecca L Roberts
Format: Article
Language:English
Published: European Medical Journal 2021-07-01
Series:European Medical Journal Rheumatology
Subjects:
crohn’s disease
dysbiosis
genetic risk factors
gut microbiota
human leukocyte antigen (hla)-b27
spondyloarthritis
spondyloarthropathies (spa)
Online Access:https://www.emjreviews.com/rheumatology/article/the-interplay-of-genes-with-the-gut-microbiota-in-the-aetiopathogenesis-of-spondyloarthropathies-and-crohns-disease-implications-for-future-therapeutic-targets-j170121/

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https://www.emjreviews.com/rheumatology/article/the-interplay-of-genes-with-the-gut-microbiota-in-the-aetiopathogenesis-of-spondyloarthropathies-and-crohns-disease-implications-for-future-therapeutic-targets-j170121/

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