Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma.

Initiation, growth, recurrence, and metastasis of head and neck squamous cell carcinomas (HNSCC) have been related to the behavior of cancer stem cells (CSC) that can be identified by their aldehyde-dehydrogenase-isoform-1 (ALDH1) activity. We quantified and enriched ALDH1(+) cells within HNSCC cell...

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Bibliographic Details
Main Authors: Chao Chen, Yan Wei, Michael Hummel, Thomas K Hoffmann, Manfred Gross, Andreas M Kaufmann, Andreas E Albers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3029362?pdf=render