Bile Acid Signaling Pathways from the Enterohepatic Circulation to the Central Nervous System

Bile acids are best known as detergents involved in the digestion of lipids. In addition, new data in the last decade have shown that bile acids also function as gut hormones capable of influencing metabolic processes via receptors such as FXR (farnesoid X receptor) and TGR5 (Takeda G protein-couple...

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Bibliographic Details
Main Authors: Kim L. Mertens, Andries Kalsbeek, Maarten R. Soeters, Hannah M. Eggink
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Neuroscience
Subjects:
CNS
FXR
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00617/full