Literature review: enteric nervous system development, genetic and epigenetic regulation in the etiology of Hirschsprung's disease

Hirschsprung's disease (HSCR) is a developmental disorder of the enteric nervous system (ENS) derived from neural crest cells (NCCs), which affects their migration, proliferation, differentiation, or preservation in the digestive tract, resulting in aganglionosis in the distal intestine. The re...

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Bibliographic Details
Main Authors: R. Diposarosa, N.A. Bustam, Edhyana Sahiratmadja, P.S. Susanto, Y. Sribudiani
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021014110