Cerebral blood flow and cerebrovascular reactivity are preserved in a mouse model of cerebral microvascular amyloidosis

Cerebral blood flow and cerebrovascular reactivity are preserved in a mouse model of cerebral microvascular amyloidosis

Impaired cerebrovascular function is an early biomarker for cerebral amyloid angiopathy (CAA), a neurovascular disease characterized by amyloid-β accumulation in the cerebral vasculature, leading to stroke and dementia. The transgenic Swedish Dutch Iowa (Tg-SwDI) mouse model develops cerebral microv...

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Bibliographic Details
Main Authors: Leon P Munting, Marc Derieppe, Ernst Suidgeest, Lydiane Hirschler, Matthias JP van Osch, Baudouin Denis de Senneville, Louise van der Weerd
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
cerebral amyloid angiopathy
cerebrovascular function
arterial spin labeling-MRI
Online Access:https://elifesciences.org/articles/61279

Internet

https://elifesciences.org/articles/61279

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