The JAK-STAT pathway controls Plasmodium vivax load in early stages of Anopheles aquasalis infection.

Malaria affects 300 million people worldwide every year and 450,000 in Brazil. In coastal areas of Brazil, the main malaria vector is Anopheles aquasalis, and Plasmodium vivax is responsible for the majority of malaria cases in the Americas. Insects possess a powerful immune system to combat infecti...

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Bibliographic Details
Main Authors: Ana C Bahia, Marina S Kubota, Antonio J Tempone, Helena R C Araújo, Bruno A M Guedes, Alessandra S Orfanó, Wanderli P Tadei, Claudia M Ríos-Velásquez, Yeon S Han, Nágila F C Secundino, Carolina Barillas-Mury, Paulo F P Pimenta, Yara M Traub-Csekö
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3206008?pdf=render