Muscle metabolic remodelling patterns in Duchenne muscular dystrophy revealed by ultra-high-resolution mass spectrometry imaging

Abstract Duchenne muscular dystrophy (DMD) is a common and severe X-linked myopathy, characterized by muscle degeneration due to altered or absent dystrophin. DMD has no effective cure, and the underlying molecular mechanisms remain incompletely understood. The aim of this study is to investigate th...

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Bibliographic Details
Main Authors: Ivana Dabaj, Justine Ferey, Florent Marguet, Vianney Gilard, Carole Basset, Youssef Bahri, Anne-Claire Brehin, Catherine Vanhulle, France Leturcq, Stéphane Marret, Annie Laquerrière, Isabelle Schmitz-Afonso, Carlos Afonso, Soumeya Bekri, Abdellah Tebani
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81090-1